Consensus map of Cx43/GJA1 gap junction channel in the presence of diC8-PIP2 (8-fold molar excess)
Release date: June 11, 2025 Resolution: 3.1 Å EM Method: Single-particle
Lee HJ, Cha HJ, Woo JS
To Be Published
Sample:
Dodecameric complex of human cx43-m257 in lipid nanodiscs (pope) in the presence of dic8-pip2 (7.5-fold molar excess) (Cellular component from Homo sapiens)
A c-terminal truncated mutant of gap junction alpha-1 protein (cx43-m257) (Protein from Homo sapiens)
EMD-38221
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Consensus map of Cx43/GJA1 gap junction channel in the presence of diC8-PIP2 (16-fold molar excess)
Release date: June 11, 2025 Resolution: 3.0 Å EM Method: Single-particle
Lee HJ, Cha HJ, Woo JS
To Be Published
Sample:
Dodecameric complex of human cx43-m257 in lipid nanodiscs (pope) in the presence of dic8-pip2 (16-fold molar excess) (Cellular component from Homo sapiens)
A c-terminal truncated mutant of gap junction alpha-1 protein (cx43-m257) (Protein from Homo sapiens)
EMD-38223
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Structure of Cx43/GJA1 gap junction intercellular channel in complex with diC8-PIP2
Release date: June 11, 2025 Resolution: 3.0 Å EM Method: Single-particle Fitted PDBs: 8xbm Q-score: 0.462
Lee HJ, Cha HJ, Woo JS
To Be Published
Sample:
Dodecameric complex of human cx43-m257 in lipid nanodiscs (pope) in the presence of dic8-pip2 (16-fold molar excess) (Cellular component from Homo sapiens)
Gap junction alpha-1 protein (29 kDa, Protein from Homo sapiens)
[(2r)-2-octanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (746 Da, Ligand)
EMD-44100
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Cryo-EM structure of the mouse TRPM3 alpha 2 channel in complex with primidone
Release date: Jan. 22, 2025 Resolution: 3.24 Å EM Method: Single-particle Fitted PDBs: 9b28 Q-score: 0.438
Yin Y, Park CG, Feng S, Guan Z, Lee HJ, Zhang F, Sharma K, Borgnia MJ, Im W, Lee SY