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› 8qvq

Electron Microscopy
4.07Å resolution

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S29P, polymorph 2

Released:
DOI: 10.2210/pdb8qvq/pdb
PDB entry 8qvq coloured by chain, front view.
PDB entry 8qvq coloured by chain, side view.
PDB entry 8qvq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ooi SA, Valli D, Maj M
Related structures: EMD-18672

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-279778 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Islet amyloid polypeptide Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Length: 38 amino acids
Theoretical weight: 3.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10997 (Residues: 34-70; Coverage: 55%)
Gene name: IAPP
Sequence domains: Calcitonin / CGRP / IAPP family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.07Å
Relevant EMDB volumes: EMD-18672
Expression system: Not provided

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